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Scientist & Sr Scientist - Mass Spec / Proteomics

  • Location: Madison, Wisconsin
  • Type: Direct Hire
  • Job #3792

Are you looking to join an explosive start-up focused on Drug Discovery and helping creating new Therapeutics? If you have a Proteomics background and expertise in Mass Spectrometry, this could be the role you're looking for – join a mission to accelerate the drug discovery of lifesaving therapeutics!

What You’ll Do

In this Scientist or Senior Scientist role, you'll be able to make an impact on day one. This is a fast-paced, entrepreneurial organization without the bureaucracy of a traditional life sciences business. As an early employee, you will collaborate with other top scientists to solve real-world customer problems to advance drug discovery. You will have the opportunity to shape the future direction of the organization and the potential to manage a team of scientists as the business grows. Individuals within this role will be able to:

  • Develop and optimize HDX, HRF, XL-MS experiments (and others as described) for applications including:
    • Epitope Mapping
    • Protein-Protein and Protein-Small Molecule Interactions
    • Structural Analysis
  • Visualize complex Proteomics datasets
  • Design and Setup the lab and lab instruments as needed
  • Provide technical presentations to clients and at conferences
  • Manager Customer projects
  • Author scientific papers
  • Write grant funding proposals
  • *This role includes future potential to manage a team of analytical and biological chemists

What You’ll Bring

There are 2 positions available, with flexibility in both degree and experience needed:

  • Minimum of BS degree and 3-4 years of industry experience, or a Masters degree with 2+ years of industry experience for a Scientist-level role.
    • Wet lab experience is required
    • Mass Spectrometry sample preparation experience is preferred, but not required
  • Minimum 4+ years of experience and strong expertise in LC-MS protein analysis for Senior roles
    • Ph.D. in analytical chemistry, biochemistry, or related field 
  • Deep understanding and proven experience in LC-MS instrumentation and troubleshooting
  • Experience in proteomic LC-MS method development and analysis
  • Ability to work independently and collaborate with team members
  • Ability to identify bottlenecks and unmet needs in analytical characterization workflows and develop solutions for customers
  • Entrepreneurial mindset with interest in taking a leadership/management role
  • Exceptional time and project management skills with the ability to own and manage multiple projects in a changing environment and meet timelines
  • Excellent communication skills and ability to speak, present and write clearly and accurately
  • Willingness to travel to conferences and customer site visits


Additional Preferred Qualifications

  • Experience or an understanding of the following techniques
    • Hydrogen/Deuterium Exchange (HDX):
    • Hydroxyl radical protein footprinting (HRF)
    • Chemical cross-linking mass spectrometry (XL-MS)
    • Site-specific labeling MS
    • Glycoprotein analysis with MS
    • In-silico structural modeling
    • Protein expression and purification
    • Membrane protein expression and purification
    • Mutagenesis
    • SEC-MALS
    • ELISA
    • Protein-Protein interaction and In Vitro binding assays
  • Experience and/or familiarity with in-silico protein structural analysis and visualization.
  • 2+ years of industry experience, especially in the field of antibody drug discovery/development
  • Hands-on experience with Thermo Orbitrap technology 
  • Familiarity with Protein Metrics software 
  • Business experience and interest
  • Demonstrated experience in developing strong customer relationships and project management


This position is based in Madison, WI and includes a full relocation package for applicable candidates. Excellent compensation package includes salary anticipated to be between $50,000 – $120,000+ dependent upon degree and experience, benefits package, stock options and performance bonuses (both cash and stock options).

If you’re looking to fully use your expertise and get on the ground floor of an exciting start-up, Apply Today!

Questions? Email Andie Dumond directly at

Carex is a Certified Minority-Owned & Woman-Owned Business. Carex Consulting Group is an equal opportunity employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, marital status, disability, gender identity or Veteran status.
To see all of our available opportunities, visit Carex at: /candidates/see-job-openings/


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